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<t>Molecular</t> features of colorectal <t>cancer</t> ( A ) and endometrial cancer ( B ). The mutational landscape and patient demographic/clinical characteristics (PD-L1 by IHC, MSI <t>comprehensive,</t> age, and sex) of the four cohorts for each cancer type were plotted using the GenVisR package of R.
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Molecular features of colorectal cancer ( A ) and endometrial cancer ( B ). The mutational landscape and patient demographic/clinical characteristics (PD-L1 by IHC, MSI comprehensive, age, and sex) of the four cohorts for each cancer type were plotted using the GenVisR package of R.

Journal: Cancer Research Communications

Article Title: Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity

doi: 10.1158/2767-9764.CRC-23-0312

Figure Lengend Snippet: Molecular features of colorectal cancer ( A ) and endometrial cancer ( B ). The mutational landscape and patient demographic/clinical characteristics (PD-L1 by IHC, MSI comprehensive, age, and sex) of the four cohorts for each cancer type were plotted using the GenVisR package of R.

Article Snippet: We conducted a retrospective analysis on the genomic profiles of 1,870 patients with colorectal cancer, 4,481 patients with endometrial cancer, and 8,190 patients with ovarian cancer that underwent genomic profiling by Caris Life Sciences (CLS) as part of their routine comprehensive tumor molecular profiling.

Techniques: